2-chloro-6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1H-benzoimidazole → HCID 178485547, compound

Participants

Reaction Steps

A mixture of 4-(3-chloro-5-hydroxymethyl-pyridin-2-yl)-piperazine-2-carboxylic acid methylamide from step (d) above (114 mg, 0.4 mmol) and 2-chloro-6-trifluoromethyl-4-(3,4,5-trifluoro-phenyl)-1H-benzoimidazole (140 mg, 0.4 mmol, Example 51b) in EtOH (1 mL) reacted under the conditions of Example 3c to give the title compound as a white solid. MS ESI, pos. ion) m/e: 599 (M+1).

Provenance & Evidence