HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triacetoxyperiodinane → HCID 57835736, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triacetoxyperiodinane | HCID 159087 | — |
| Reactant | Oxazol-5-yl(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanol | HCID 57835730 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57835736 | HCID 57835736 | 42% |
Reaction Steps
Dess-Martin periodinane (25 g, 60 mmol) was added to a solution of 75.1 (17 g crude, ˜50 mmol) in DCM (200 mL). After 1 hour, the reaction mixture was concentrated with silica gel and chromatographed (silica gel, 1:2 EtOAc/hexane) to obtain compound 75.2 (5.74 g, 21 mmol). MS ESI (pos.) m/e: 274.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582803B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7366ea8eb5ae4cf1892a780e2efeb851 |
| Source note | uspto-grants-2009_09 |