1,1-Dimethylhydrazine → HCID 69063730, compound

HRID 731339Notes

Reaction equation

HRID 731339 reaction equation
[CH2:1]([O:3][C:4]([CH:6]1[CH2:10][CH2:9][CH2:8][C:7]1=O)=[O:5])[CH3:2].[CH3:12][N:13]([CH3:15])[NH2:14]>C(O)C>[CH3:12][N:13]([CH3:15])[N:14]=[C:7]1[CH2:8][CH2:9][CH2:10][CH:6]1[C:4]([O:3][CH2:1][CH3:2])=[O:5]

Participants

4

Reactant 2

HCID 59761,1-DimethylhydrazineHCID 69136Ethyl 2-oxocyclopentanecarboxylate

Product 1

HCID 69063730HCID 69063730, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
25 °C

Procedure

2-Oxo-cyclopentanecarboxylic acid ethyl ester (1.00 mL, 6.91 mmol) was dissolved in ethanol (10 mL). N,N-Dimethylhydrazine (0.53 mL, 6.91 mmol) was added. The reaction was stirred at 25° C. for 16 h. The resulting mixture was concentrated in vacuo to afford the crude product, ethyl 2-(2,2-dimethylhydrazono)cyclopentane-carboxylate, which was used in the next step without further purification. LC-MS (ESI) calcd for C10H18N2O2 198.26, found 199.2 [M+H+].

Workup

  1. concentrationThe resulting mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-07d24853394b489392cbea85533cc0c1
Source dataset
uspto-grants-2009_09
Patent number
US07582626B2

Reaction notes

Loading…