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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 731425Generated: October 31, 2026

Hydrochloric Acid → HCID 178495639, compound

https://huagongshe.com/reaction/731425

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178473156HCID 178473156—
SolventMethanolHCID 887—
ProductHCID 178495639HCID 178495639—

Reaction Steps

{2-[3-Cyclohexyl-3-(trans-4-methoxymethyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was dissolved in methanol (10 mL) and 1N sodium hydroxide (5 mL) was added. Stirred at room temperature for 3 h then acidified with 1N hydrochloric acid. The white precipitate was filtered and dried to give the title compound (97 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582769B2
Source datasetuspto-grants-2009_09
ORD IDord-be3d61a7be60499ebaa96419435d4dde
Source noteuspto-grants-2009_09