Cyclohexyl-(4-phenyl-cyclohexyl)-amine → 2-{2-[3-Cyclohexyl-3-(4-phenyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acid

Participants

Role	Name	HCID	Charge
Reactant	Cyclohexyl-(4-phenyl-cyclohexyl)-amine	HCID 19381486	—
Reactant	Ethyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoate	HCID 57481427	—
Reactant	HCID 178455810	HCID 178455810	—
Product	2-{2-[3-Cyclohexyl-3-(4-phenyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acid	HCID 57688203	—

Reaction Steps

Prepared in a similar manner to {2-[3-cyclopentyl-3-(trans-4-ethyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid via cyclohexyl-(4-phenyl-cyclohexyl)-amine and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07582769B2
Source dataset	uspto-grants-2009_09
ORD ID	ord-f662987a6f5e4fda97ef74c293e7b8d1
Source note	uspto-grants-2009_09