HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178526035, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178473155 | HCID 178473155 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178526035 | HCID 178526035 | 96.3% |
Reaction Steps
80 mg of {2-[3-cyclohexyl-3-(trans-4-phenoxymethyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was dissolved in tetrahydrofuran (1 mL) and 1N sodium hydroxide (1 mL) was added. Stirred at room temperature for 2 h then acidified with 1N hydrochloric acid. White precipitate filtered and dried to give the title compound (73 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582769B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-ac15c23c5bf54fbb8d904eea2355661a |
| Source note | uspto-grants-2009_09 |