HCID 178459264, compound → HCID 178459269, compound

HRID 731489Notes

Reaction equation

HRID 731489 reaction equation
C1(N([C@H]2CC[C@H](OC)CC2)[C:7](=[O:19])[NH:8][C:9]2[S:10][C:11]([S:14][CH2:15][C:16]([OH:18])=[O:17])=[CH:12][N:13]=2)CCCC1.[CH:28]1([NH:34][C@H:35]2[CH2:40][CH2:39][C@@H:38]([O:41][CH2:42][CH2:43][CH3:44])[CH2:37][CH2:36]2)[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>C(OC(=O)C)C>[CH:28]1([N:34]([C@H:35]2[CH2:40][CH2:39][C@@H:38]([O:41][CH2:42][CH2:43][CH3:44])[CH2:37][CH2:36]2)[C:7](=[O:19])[NH:8][C:9]2[S:10][C:11]([S:14][CH2:15][C:16]([OH:18])=[O:17])=[CH:12][N:13]=2)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1

Participants

4

Reactant 2

HCID 178459264HCID 178459264, compoundHCID 178496618HCID 178496618, compound

Product 1

HCID 178459269HCID 178459269, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared in a similar manner as {2-[3-cyclopentyl-3-(trans-4-methoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using cyclohexyl-cis-(4-propoxycyclohexyl)-amine and amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

Sources & evidence

ORD record
ord-cd2aa07a78ea4b638a141e3ff434b8ad
Source dataset
uspto-grants-2009_09
Patent number
US07582769B2

Reaction notes

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