Methylamine → HCID 178485802, compound

HRID 731493Notes

Reaction equation

HRID 731493 reaction equation
[CH:1]1([N:7]([C@H:29]2[CH2:34][CH2:33][C@H:32]([CH3:35])[CH2:31][CH2:30]2)[C:8](=[O:28])[NH:9][C:10]2[S:11][C:12]([S:15]([N:18](C)[CH2:19][C:20]([N:22](CC)[CH2:23]C)=[O:21])(=[O:17])=[O:16])=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C1(N([C@H]2CC[C@H](C)CC2)C(=O)NC2SC(S(NCC(O)=O)(=O)=O)=CN=2)CCCCC1.CN>>[CH:1]1([N:7]([C@H:29]2[CH2:34][CH2:33][C@H:32]([CH3:35])[CH2:31][CH2:30]2)[C:8](=[O:28])[NH:9][C:10]2[S:11][C:12]([S:15]([NH:18][CH2:19][C:20]([NH:22][CH3:23])=[O:21])(=[O:16])=[O:17])=[CH:13][N:14]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 178461397HCID 178461397, compoundHCID 178464221HCID 178464221, compound

Product 1

HCID 178485802HCID 178485802, compound

Procedure

The title compound was prepared in a similar manner to 2-({2-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazole-5-sulfonyl}-methyl-amino)-N,N-diethyl-acetamide using {2-[3-cyclohexyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazole-5-sulfonylamino}-acetic acid and methylamine.

Sources & evidence

ORD record
ord-7d4984f30de8486181020fa00475a444
Source dataset
uspto-grants-2009_09
Patent number
US07582769B2

Reaction notes

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