反应详情

温度

50 °C

The product from step (f) (0.339 g) was suspended in methanol (32 ml). Potasium hydroxide (0.088 g) added and mixture stirred at 50° C. for 20 minutes. Neutralised with 2N HCl and solvents removed in vacuo to give an orange residue. Water added to remove inorganics and the yellow solid was collected by filtration to give 0.3 g of desired product. 90% yield.

1. customNeutralised with 2N HCl and solvents removed in vacuo
2. customto give an orange residue
3. customto remove inorganics
4. filtrationthe yellow solid was collected by filtration