Furfurylamine → HCID 24738677, compound

HRID 731631Notes

Reaction equation

[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[C:13]1[N:14]=[C:15]2[CH:20]=[C:19]([C:21]([OH:23])=O)[CH:18]=[CH:17][N:16]2[CH:24]=1.[CH2:25]([NH2:31])[C:26]1[O:30][CH:29]=[CH:28][CH:27]=1>>[O:30]1[CH:29]=[CH:28][CH:27]=[C:26]1[CH2:25][NH:31][C:21]([C:19]1[CH:18]=[CH:17][N:16]2[CH:24]=[C:13]([C:3]3[C:4]([C:7]4[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=4)=[N:5][O:6][C:2]=3[CH3:1])[N:14]=[C:15]2[CH:20]=1)=[O:23]

Participants

Reactant 2

HCID 3438Furfurylamine

HCID 69067892HCID 69067892, compound

Product 1

HCID 24738677HCID 24738677, compoundYield 72%

Procedure

As described for Example 11b, 2-(5-methyl-3-phenyl-isoxazol-4-yl)-imidazo[1,2-a]pyridine-7-carboxylic acid (64 mg, 0.2 mmol) was converted, using furfurylamine instead of aminomethylcyclopropane, to the title compound (57 mg, 72%) which was obtained as a yellow foam. MS: m/e=399.1 [M+H]+.

Sources & evidence

ORD record: ord-adbed8b9c36b43fc8bc5b5d7d06f1abe
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07585874B2

Reaction notes

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