m-Aminoacetanilide → HCID 23112256, compound

HRID 731948Notes

Reaction equation

HRID 731948 reaction equation
NC1C=C(NC(=O)C)C=CC=1.C(Cl)(=O)C=CC1C=CC=CC=1.[C:23]([NH:26][C:27]1[CH:28]=[C:29]([NH:33][C:34](=[O:43])[CH:35]=[CH:36]C2C=CC=CC=2)[CH:30]=[CH:31][CH:32]=1)(=[O:25])[CH3:24].[Cl-].[Al+3].[Cl-].[Cl-]>>[O:43]=[C:34]1[CH:35]=[CH:36][C:30]2[C:29](=[CH:28][C:27]([NH:26][C:23](=[O:25])[CH3:24])=[CH:32][CH:31]=2)[NH:33]1

Participants

5

Reactant 4

HCID 7604m-AminoacetanilideHCID 660233-Phenylprop-2-enoyl chlorideHCID 764035HCID 764035, compoundHCID 6451240Aluminum(III) Chloride

Product 1

HCID 23112256HCID 23112256, compound

Procedure

N-(3-Aminophenyl)acetamide was treated with cinnamoyl chloride in the presence of a base and then the resulting N-[3-(acetylamino)phenyl]-3-phenylacrylamide was treated with aluminum chloride to obtain N-(2-oxo-1,2-dihydroquinolin-7-yl)acetamide.

Sources & evidence

ORD record
ord-24aaf8c8c83e4feb83396135b8749641
Source dataset
uspto-grants-2009_09
Patent number
US07585878B2

Reaction notes

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