反应详情

4-Methoxybenzonitrile and 24% hydrochloric acid in EtOH were mixed at 0° C. This mixture was left stirring at r.t. o.n., followed by concentration in-vacuo. The isolated residue was triturated with Et2O to isolate the title compound (1.25 g). 1H-NMR: 12.3 (br. s, 1H), 11.6 (br. s, 1H), 8.43 (d, 2H), 7.04 (d, 2H), 4.91 (t, 3H), 3.90 (s, 3H), 1.61 (t, 3H).

1. waitThis mixture was left
2. concentration, followed by concentration in-vacuo
3. customThe isolated residue was triturated with Et2O