HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoate → HCID 23143320, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoate | HCID 23082888 | — |
| Reactant | (4-([(4-Phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}phenyl)methanol | HCID 23143295 | — |
| Product | HCID 23143320 | HCID 23143320 | 41% |
Reaction Steps
The title compound was synthesized in the same manner as in Example 8 from (4-{[(4-phenyl-1,3-thiazol-2-yl)(2-pyridin-2-ylethyl)amino]methyl}phenyl)methanol and ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoate by Mitsunobu reaction (yield 41%). Yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585880B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-e6aae06c69244b159fdeb88e579a78c8 |
| Source note | uspto-grants-2009_09 |