4-Cyanophenol → 4-((5-Chloropentyl)oxy)benzonitrile

HRID 732239Notes

Reaction equation

HRID 732239 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.Br[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][Cl:16]>>[Cl:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][O:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 130194-CyanophenolHCID 960701-Bromo-5-chloropentane

Product 1

HCID 193815104-((5-Chloropentyl)oxy)benzonitrile

Procedure

reacting 4-hydroxy-benzonitrile (7) with 1-bromo-5-chloropentane to afford 4-(5-chloro-pentoxy)-benzonitrile (8), which is then reacted with iodide, to prepare 4-(5-iodo-pentoxy)-benzonitrile (9),

Sources & evidence

ORD record
ord-2099f230d6ee48a4b9849d38f9caf921
Source dataset
uspto-grants-2009_09
Patent number
US07585979B2

Reaction notes

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