反应详情

Dissolve 5-(furan-2-carbonyl)-N-methyl-N-propyl-isophthalamic acid methyl ester (100 mg, 0.3 mmol) in methanol (10 mL). Add dropwise 2 N NaOH (0.225 mL) and stir overnight at room temperature. Acidify the mixture to about pH=6 by 5 N HCl and concentrate to near dryness. Dilute the residue with ethyl acetate and wash by saturated aqueous sodium chloride solution, dry (magnesium sulfate) and concentrate.

1. concentrationconcentrate to near dryness
2. additionDilute the residue with ethyl acetate
3. washwash by saturated aqueous sodium chloride solution
4. dry with materialdry (magnesium sulfate)
5. concentrationconcentrate