反应详情

Dissolve N-methyl-5-(2-methylacryloyl)-N-propyl-isophthalamic acid methyl ester (80 mg, 0.26 mmol) in ethyl acetate (25 mL) under nitrogen. Add Raney® nickel (100 mg) and hydrogenate the reaction for 2 h at room temperature under an atmosphere of hydrogen gas (40 psi). Filter the reaction and concentrate to give the crude title product.

1. customthe reaction for 2 h at room temperature under an atmosphere of hydrogen gas (40 psi)
2. filtrationFilter
3. customthe reaction
4. concentrationconcentrate