HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68815198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68816253 | HCID 68816253 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68815198 | HCID 68815198 | — |
Reaction Steps
React (2R,4R)-2-[(1S,2S)-2-Acetylamino-3-(3,5-difluorophenyl)-1-hydroxypropyl]-4-(3-methoxy-phenoxy)-pyrrolidine-1-carboxylic acid tert-butyl ester With 4M HCl in dioxane essentially as described in EXAMPLE 1 to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585885B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-6af6eefc63cc4a13bb28cec3798c4226 |
| Source note | uspto-grants-2009_09 |