HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131727624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 68818146 | HCID 68818146 | — |
| Product | HCID 131727624 | HCID 131727624 | 93% |
Reaction Steps
Add HCl 4M in dioxane (0.861 mL, 3.4 mmol) to (R)-2-[(4S,5S)-3-Acetyl-4-(3,5-difluoro-benzyl)-2,2-dimethyl-oxazolidin-5-yl]-4-[1-methoxycarbonyl-meth-(Z)-ylidene]-pyrrolidine-1-carboxylic acid tert-butyl ester (0.024 g, 0.046 mmol). Stir overnight. Concentrate under reduced pressure to provide the title compound (0.021 g, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585885B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-f37ddd30d69f42b8bee6653ec278a1b7 |
| Source note | uspto-grants-2009_09 |