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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 732608Generated: October 28, 2026

Hydrochloric Acid → HCID 131727624, compound

https://huagongshe.com/reaction/732608

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 68818146HCID 68818146—
ProductHCID 131727624HCID 13172762493%

Reaction Steps

Add HCl 4M in dioxane (0.861 mL, 3.4 mmol) to (R)-2-[(4S,5S)-3-Acetyl-4-(3,5-difluoro-benzyl)-2,2-dimethyl-oxazolidin-5-yl]-4-[1-methoxycarbonyl-meth-(Z)-ylidene]-pyrrolidine-1-carboxylic acid tert-butyl ester (0.024 g, 0.046 mmol). Stir overnight. Concentrate under reduced pressure to provide the title compound (0.021 g, 93%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07585885B2
Source datasetuspto-grants-2009_09
ORD IDord-f37ddd30d69f42b8bee6653ec278a1b7
Source noteuspto-grants-2009_09