HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68814268, compound → HCID 68815253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68814268 | HCID 68814268 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68815253 | HCID 68815253 | 76% |
Reaction Steps
Stir a solution of (2R,4R)-2-[(4S,5S)-3-acetyl-4-(3,5-difluoro-benzyl)-2,2-dimethyl-oxazolidin-5-yl]-4-(3-methyl-but-2-enyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester and 10% palladium on carbon (0.02 g) in methanol (5 mL) under one atmosphere of hydrogen gas for 18 hours. Filter and evaporate to give the desired compound as a foam (0.081 g, 76%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585885B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-08ec74e8ac044e19a18a50f278fdc1c4 |
| Source note | uspto-grants-2009_09 |