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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 732613Generated: October 28, 2026

HCID 68814268, compound → HCID 68815253, compound

https://huagongshe.com/reaction/732613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68814268HCID 68814268—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 68815253HCID 6881525376%

Reaction Steps

Stir a solution of (2R,4R)-2-[(4S,5S)-3-acetyl-4-(3,5-difluoro-benzyl)-2,2-dimethyl-oxazolidin-5-yl]-4-(3-methyl-but-2-enyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester and 10% palladium on carbon (0.02 g) in methanol (5 mL) under one atmosphere of hydrogen gas for 18 hours. Filter and evaporate to give the desired compound as a foam (0.081 g, 76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07585885B2
Source datasetuspto-grants-2009_09
ORD IDord-08ec74e8ac044e19a18a50f278fdc1c4
Source noteuspto-grants-2009_09