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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 732616Generated: October 30, 2026

Hydrochloric Acid → HCID 68818090, compound

https://huagongshe.com/reaction/732616

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68815214HCID 68815214—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68818090HCID 68818090100%

Reaction Steps

Add 4M hydrogen chloride in dioxane (5 mL) to (2R,4R)-2-[(4S,5S)-3-acetyl-4-(3,5-difluoro-benzyl)-2,2-dimethyl-oxazolidin-5-yl]-4-(3-hydroxy-3-methyl-butoxy)-pyrrolidine-1-carboxylic acid tert-butyl ester (0.11 g, 0.207 mmol). Stir 4 hours and evaporate to give the title compound as a foam (0.102 g, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07585885B2
Source datasetuspto-grants-2009_09
ORD IDord-338c2d09530b440594b9f97ea381dc24
Source noteuspto-grants-2009_09