HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-oxo-4-phenylpyrrolidine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate | HCID 313653 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-oxo-4-phenylpyrrolidine-3-carboxylic acid | HCID 2836868 | — |
Reaction Steps
1 M sodium hydroxide aqueous solution was added at room temperature to a methanol solution of ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate (Wako Pure Chemical Industries (Wako), Japan) and stirred for 13Hours. The reaction solution was acidified by adding 1 M hydrochloric acid, and the thus precipitated solid was collected by filtration and dried to obtain 2-oxo-4-phenylpyrrolidine-3-carboxylic acid. FP: 206.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07585886B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-96a333b29e1447fbb71a448f4acc9a4e |
| Source note | uspto-grants-2009_09 |