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HRID732661

反应详情

EQUATION

反应方程式

HRID 732661 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)[Si](C)(C)Cl
HCID28928

Chloro(1,1-dimethylethyl)dimethylsilane

C6H15ClSi

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：OCC1CCN(Cc2ccccc2)C1
HCID5176654

(1-benzylpyrrolidin-3-yl)methanol

C12H17NO

PRODUCTS

生成物

1
结构：CC(C)(C)[Si](C)(C)OCC1CCN(Cc2ccccc2)C1
HCID19914927

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

Diisopropylethylamine and tert-butyldimethyl-chlorosilane were added in that order to a chloroform solution of (1-benzylpyrrolidin-3-yl)methanol and stirred at room temperature for 5Hours. Thereafter, its work-up and purification were carried out in the standard method to obtain 1-benzyl-3-({[tert-butyl(dimethyl)silyl]oxy}methyl]pyrrolidine. EP: 306.

WORKUP

后处理

  1. customThereafter, its work-up and purification