Tetrabutylammonium Fluoride → HCID 62372909, compound

HRID 732662Notes

Reaction equation

HRID 732662 reaction equation
CCCC[N+](CCCC)(CCCC)CCCC.[F-].[Si]([O:26][CH2:27][CH:28]1[CH2:32][CH2:31][N:30]([C:33](=[O:38])[C:34]([F:37])([F:36])[F:35])[CH2:29]1)(C(C)(C)C)(C)C>C1COCC1>[F:37][C:34]([F:35])([F:36])[C:33]([N:30]1[CH2:31][CH2:32][CH:28]([CH2:27][OH:26])[CH2:29]1)=[O:38]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 86628539HCID 86628539, compound

Product 1

HCID 62372909HCID 62372909, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

TBAF was added to a THF solution of 3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1-(trifluoroacetyl)pyrrolidine and stirred overnight at room temperature. Thereafter, its work-up and purification were carried out in the standard method to obtain [1-(trifluoroacetyl)pyrrolidin-3-yl]methanol. EP: 198.

Workup

  1. customThereafter, its work-up and purification

Sources & evidence

ORD record
ord-f1564a3a00924549bac36c8eb85e3fd5
Source dataset
uspto-grants-2009_09
Patent number
US07585886B2

Reaction notes

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