HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 9813851, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | Ethyl 5-Amino-7-(2-Furyl)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-3-Ylacetate | HCID 9921985 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 9813851 | HCID 9813851 | 85% |
Reaction Steps
A solution of ethyl 5-amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-ylacetate (547 mg, 1.89 mmol) in MeOH (5 mL) was treated with aqueous NaOH (2 mL, 2-M, 4 mmol), refluxed for 10 min, cooled, acidified with aqueous HCl (1-M), filtered and dried to give the title compound (417 mg, 85%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589097B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-ae682b777df547e3beba023d3e9e2b89 |
| Source note | uspto-grants-2009_09 |