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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 733129Generated: October 29, 2026

2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → Ethyl-5-methyl-1-[2'-(trifluoromethoxy)-1,1'-biphenyl-3-yl]-1H-pyrazole-3-carboxylate

https://huagongshe.com/reaction/733129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 2777204—
ReactantEthyl 1-(3-bromophenyl)-5-methyl-1h-pyrazole-3-carboxylateHCID 18549277—
ProductEthyl-5-methyl-1-[2'-(trifluoromethoxy)-1,1'-biphenyl-3-yl]-1H-pyrazole-3-carboxylateHCID 11417896—

Reaction Steps

The titled compound was prepared by reacting ethyl 1-(3-bromophenyl)-5-methyl-1H-pyrazole-3-carboxylate (from Step 1 of EXAMPLE 1) with 2-(Trifluoromethoxy)phenylboronic acid (from Step 3 of EXAMPLE 1) under the reaction condition described in Step 4 of EXAMPLE 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07589116B2
Source datasetuspto-grants-2009_09
ORD IDord-42d9341cdd6d427aad641ffc9503895f
Source noteuspto-grants-2009_09