Diisobutylaluminum hydride → HCID 11393904, compound

HRID 733140Notes

Reaction equation

HRID 733140 reaction equation
[CH3:1][C:2]1[CH:6]=[C:5]([C:7](OCC)=[O:8])[N:4]([C:12]2[CH:13]=[C:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[O:24][C:25]([F:28])([F:27])[F:26])[CH:15]=[CH:16][CH:17]=2)[N:3]=1.CC(C[AlH]CC(C)C)C>>[CH3:1][C:2]1[CH:6]=[C:5]([CH2:7][OH:8])[N:4]([C:12]2[CH:13]=[C:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[O:24][C:25]([F:27])([F:26])[F:28])[CH:15]=[CH:16][CH:17]=2)[N:3]=1

Participants

3

Reactant 2

HCID 14487Diisobutylaluminum hydrideHCID 11429222HCID 11429222, compound

Product 1

HCID 11393904HCID 11393904, compound

Procedure

The titled compound was prepared by reacting ethyl 3-methyl-1-[2′-(trifluoromethoxy)-1,1′-biphenyl-3-yl]-1H-pyrazole-5-carboxylate (EXAMPLE 21) with DIBALH in a manner described in EXAMPLE 123. MS (ESI): m/e 349 (M+1)+

Sources & evidence

ORD record
ord-9b30809b072447bab4dcd9279bf7ae56
Source dataset
uspto-grants-2009_09
Patent number
US07589116B2

Reaction notes

Loading…