5-(Trifluoromethyl)isobenzofuran-1,3-dione → HCID 22025409, compound

HRID 733269Notes

Reaction equation

HRID 733269 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[N:8]([CH2:11][CH2:12][C:13]([F:16])([F:15])[F:14])[C:6](=[O:7])[C:5]2=[CH:17][CH:18]=1.[F:19][C:20]([F:33])([F:32])C1C=C2C(=O)OC(=O)C2=CC=1>C(OCC)(=O)C>[F:19][C:20]([F:33])([F:32])[C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[N:8]([CH2:11][CH2:12][C:13]([F:16])([F:15])[F:14])[C:6](=[O:7])[C:5]2=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 127177895-(Trifluoromethyl)isobenzofuran-1,3-dioneHCID 22025412HCID 22025412, compound

Product 1

HCID 22025409HCID 22025409, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4-Trifluoromethyl-N-(3,3,3-trifluoropropyl)phthalimide is prepared in a similar manner to 4-chloro-N-(3,3,3-trifluoropropyl)phthalimide described in Example 26, starting with 4-trifluoromethylphthalic anhydride, Rf=0.12, (thin layer chromatography on silica gel, eluent: ethyl acetate).

Sources & evidence

ORD record
ord-da743b97814e4a24b79d5b8fed5ce93b
Source dataset
uspto-grants-2009_09
Patent number
US07589117B2

Reaction notes

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