Benzaldehyde → HCID 9997339, compound

HRID 733310Notes

Reaction equation

HRID 733310 reaction equation
[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH2:12][CH2:13][N:14]([CH3:16])C)=[C:9]([OH:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(=O)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:16]([NH:14][CH2:13][CH2:12][C:8]1[C:7]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:10][C:9]=1[OH:11])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 10331103HCID 10331103, compound

Product 1

HCID 9997339HCID 9997339, compound

Procedure

The product of Example 75 (0.143 g) was treated with 0.060 g (0.58 mmol) of benzaldehyde according to the procedure described in Example 3. The product was purified on a silica gel flash chromatography column eluted with 5% isopropanol in hexane. Evaporation of the purified fractions and drying in vacuo afforded the title compound.

Workup

  1. customThe product was purified on a silica gel flash chromatography column
  2. washeluted with 5% isopropanol in hexane
  3. customEvaporation of the purified fractions
  4. customdrying in vacuo

Sources & evidence

ORD record
ord-2af683ec541a42e78417ae05d08ab2fe
Source dataset
uspto-grants-2009_09
Patent number
US07589127B2

Reaction notes

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