反应详情

Using an adaptation of the method described in Procedure 23, substituting 9-[8-(2,2,2-trifluoroacetyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-9H-xanthene-3-carbonitrile, 3j for 2,2,2-trifluoro-1-{3-[3-(1H-tetrazol-5-yl)-9H-xanthen-9-yl]-8-aza-bicyclo-[3.2.1]oct-8-yl}-ethanone, 4j, the title compound 9-(8-aza-bicyclo[3.2.1]oct-3-yl)-9H-xanthene-3-carbonitrile, 1m was obtained.