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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 733420Generated: November 1, 2026

9-[8-(2,2,2-Trifluoroacetyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-9H-xanthene-3-carbonitrile → 9-(8-Aza-bicyclo[3.2.1]oct-3-yl)-9H-xanthene-3-carbonitrile

https://huagongshe.com/reaction/733420

Reaction equation

Participants

RoleNameHCIDCharge
Reactant9-[8-(2,2,2-Trifluoroacetyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-9H-xanthene-3-carbonitrileHCID 57839255—
ReactantHCID 178521660HCID 178521660—
Product9-(8-Aza-bicyclo[3.2.1]oct-3-yl)-9H-xanthene-3-carbonitrileHCID 57839270—

Reaction Steps

Using an adaptation of the method described in Procedure 23, substituting 9-[8-(2,2,2-trifluoroacetyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-9H-xanthene-3-carbonitrile, 3j for 2,2,2-trifluoro-1-{3-[3-(1H-tetrazol-5-yl)-9H-xanthen-9-yl]-8-aza-bicyclo-[3.2.1]oct-8-yl}-ethanone, 4j, the title compound 9-(8-aza-bicyclo[3.2.1]oct-3-yl)-9H-xanthene-3-carbonitrile, 1m was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07589104B2
Source datasetuspto-grants-2009_09
ORD IDord-99a357edefa746c090d172e60f886f82
Source noteuspto-grants-2009_09