HRID733537

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID64801

Benzenepropanoyl chloride

C9H9ClO

结构：CCCCCCCCC#Cc1ccc(CNc2ccc(/C=C/C(=O)OCC)cc2)cc1

HCID11200896

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCC#Cc1ccc(CN(C(=O)CCc2ccccc2)c2ccc(/C=C/C(=O)OCC)cc2)cc1

HCID86612441

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure E using of ethyl (2E)-3-{4-[(4-dec-1-ynylbenzyl)amino]phenyl}acrylate and 3-phenylpropanoyl chloride (58%). M+ (ESI): 560.6. HPLC, Rt: 6.4 min (purity: 98.7%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-157d556a67a3415cb4c22b39522c5f6b
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07589232B2
来源说明: uspto-grants-2009_09

反应 SMILES

[C:1]([C:11]1[CH:31]=[CH:30][C:14]([CH2:15][NH:16][C:17]2[CH:22]=[CH:21][C:20](/[CH:23]=[CH:24]/[C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:19][CH:18]=2)=[CH:13][CH:12]=1)#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:32]1([CH2:38][CH2:39][C:40](Cl)=[O:41])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[C:1]([C:11]1[CH:31]=[CH:30][C:14]([CH2:15][N:16]([C:40](=[O:41])[CH2:39][CH2:38][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[C:17]2[CH:18]=[CH:19][C:20](/[CH:23]=[CH:24]/[C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:21][CH:22]=2)=[CH:13][CH:12]=1)#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]