4-Pentynoic acid → HCID 11398066, compound

HRID 733578Notes

Reaction equation

HRID 733578 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[C:12][C:13]2[CH:33]=[CH:32][C:16]([CH2:17][NH:18][CH2:19][C:20]3[CH:31]=[CH:30][C:23]([O:24][CH2:25][C:26]([O:28]C)=[O:27])=[CH:22][CH:21]=3)=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].[C:34](O)(=[O:39])[CH2:35][CH2:36][C:37]#[CH:38]>>[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[C:12][C:13]2[CH:14]=[CH:15][C:16]([CH2:17][N:18]([CH2:19][C:20]3[CH:21]=[CH:22][C:23]([O:24][CH2:25][C:26]([OH:28])=[O:27])=[CH:30][CH:31]=3)[C:34](=[O:39])[CH2:35][CH2:36][C:37]#[CH:38])=[CH:32][CH:33]=2)=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 224644-Pentynoic acidHCID 57554567Methyl {4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]phenoxy}acetate

Product 1

HCID 11398066HCID 11398066, compound

Procedure

The titled compound was prepared following the procedure H using methyl {4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]phenoxy}acetate and pent-4-ynoic acid as a yellow oil (99%). HPLC, Rt: 5.63 min (Purity: 98.6%).

Sources & evidence

ORD record
ord-f6c5142687d34e5599fdfbe89a55c7b9
Source dataset
uspto-grants-2009_09
Patent number
US07589232B2

Reaction notes

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