HRID733647

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2757302

4-tert-Butylphenylacetylene

C12H14

结构：CC1(C)OC(=O)c2ccc(N(Cc3ccc(Br)cc3)C(=O)CCC3CCCC3)cc2O1

HCID57841396

未命名化合物

PRODUCTS

生成物

结构：CC1(C)OC(=O)c2ccc(N(Cc3ccc(C#Cc4ccc(C(C)(C)C)cc4)cc3)C(=O)CCC3CCCC3)cc2O1

HCID57841343

未命名化合物

PROCEDURE

实验过程

The titled compound was prepared following the procedure N using N-(4-bromobenzyl)-3-cyclopentyl-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-7-yl)propanamide and 4-(tert-butyl)-phenylacetylene as a beige powder (65%). M1(ESI): 564.2. HPLC, Rt: 6.39 min (Purity: 98.9%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6ecbaa5497874e98abacc77d3c665988
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07589232B2
来源说明: uspto-grants-2009_09

反应 SMILES

Br[C:2]1[CH:31]=[CH:30][C:5]([CH2:6][N:7]([C:17]2[CH:18]=[CH:19][C:20]3[C:25](=[O:26])[O:24][C:23]([CH3:28])([CH3:27])[O:22][C:21]=3[CH:29]=2)[C:8](=[O:16])[CH2:9][CH2:10][CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:4][CH:3]=1.[C:32]([C:36]1[CH:41]=[CH:40][C:39]([C:42]#[CH:43])=[CH:38][CH:37]=1)([CH3:35])([CH3:34])[CH3:33]>>[C:32]([C:36]1[CH:37]=[CH:38][C:39]([C:42]#[C:43][C:2]2[CH:3]=[CH:4][C:5]([CH2:6][N:7]([C:17]3[CH:18]=[CH:19][C:20]4[C:25](=[O:26])[O:24][C:23]([CH3:27])([CH3:28])[O:22][C:21]=4[CH:29]=3)[C:8](=[O:16])[CH2:9][CH2:10][CH:11]3[CH2:12][CH2:13][CH2:14][CH2:15]3)=[CH:30][CH:31]=2)=[CH:40][CH:41]=1)([CH3:35])([CH3:34])[CH3:33]