HRID733648

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2775123

1-ethynyl-4-propoxybenzene

C11H12O

结构：CC1(C)OC(=O)c2ccc(N(Cc3ccc(Br)cc3)C(=O)CCC3CCCC3)cc2O1

HCID57841396

未命名化合物

PRODUCTS

生成物

结构：CCCOc1ccc(C#Cc2ccc(CN(C(=O)CCC3CCCC3)c3ccc4c(c3)OC(C)(C)OC4=O)cc2)cc1

HCID57841355

未命名化合物

PROCEDURE

实验过程

The titled compound was prepared following the procedure N using N-(4-bromobenzyl)-3-cyclopentyl-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-7-yl)propanamide and 4-(propoxy)-phenylacetylene as a beige powder (59%). M+ (ESI): 566.2. HPLC, Rt: 6.17 min (Purity: 97.7%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d4799322ba874799bc66d3a3dd5a8c9e
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07589232B2
来源说明: uspto-grants-2009_09

反应 SMILES

Br[C:2]1[CH:31]=[CH:30][C:5]([CH2:6][N:7]([C:17]2[CH:18]=[CH:19][C:20]3[C:25](=[O:26])[O:24][C:23]([CH3:28])([CH3:27])[O:22][C:21]=3[CH:29]=2)[C:8](=[O:16])[CH2:9][CH2:10][CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:4][CH:3]=1.[CH2:32]([O:35][C:36]1[CH:41]=[CH:40][C:39]([C:42]#[CH:43])=[CH:38][CH:37]=1)[CH2:33][CH3:34]>>[CH:11]1([CH2:10][CH2:9][C:8]([N:7]([C:17]2[CH:18]=[CH:19][C:20]3[C:25](=[O:26])[O:24][C:23]([CH3:27])([CH3:28])[O:22][C:21]=3[CH:29]=2)[CH2:6][C:5]2[CH:4]=[CH:3][C:2]([C:43]#[C:42][C:39]3[CH:40]=[CH:41][C:36]([O:35][CH2:32][CH2:33][CH3:34])=[CH:37][CH:38]=3)=[CH:31][CH:30]=2)=[O:16])[CH2:15][CH2:14][CH2:13][CH2:12]1