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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 733681Generated: October 25, 2026

1-Cyclobutylmethanamine hydrochloride → 7-chloro-N-(cyclobutylmethyl)-1H-pyrrolo[2,3-c]pyridine-4-carboxamide

https://huagongshe.com/reaction/733681

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclobutylmethanamine hydrochlorideHCID 21707944—
Reactant7-chloro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acidHCID 57840843—
Product7-chloro-N-(cyclobutylmethyl)-1H-pyrrolo[2,3-c]pyridine-4-carboxamideHCID 57840782—

Reaction Steps

Prepared in a similar manner to Example 19 (e) from 7-chloro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid using cyclobutylmethylamine hydrochloride (46 mg) instead of tetrahydro-pyran-4-ylmethylamine to give the title compound (39 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07589206B2
Source datasetuspto-grants-2009_09
ORD IDord-8ea13bc326cc4625be04bed8be36d4b7
Source noteuspto-grants-2009_09