HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyaniline → HCID 57840939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | 1,1-Dimethylethyl 7-chloro-3-methyl-4-(1-piperidinylcarbonyl)-1H-pyrrolo[2,3-c]pyridine-1-carboxylate | HCID 57840991 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 57840939 | HCID 57840939 | — |
Reaction Steps
Prepared in a similar manner to Example 4(d) from 7-chloro-3-methyl-4-(1-piperidin-1-yl-methanoyl)-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester (90 mg) and using 3-methoxyaniline (54 ul) instead of 3-bromoaniline and heating for 15 rather than 30 minutes. Isolated by MDAP rather than trituration with diethyl ether to give 1-[7-(3-methoxy-phenylamino)-3-methyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-piperidin-1-yl-methanone (65 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589206B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7f43ed7d561147d9bfa3a24f23d604b8 |
| Source note | uspto-grants-2009_09 |