HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, ((2-bromoethoxy)methyl)- → 5-Fluoropyrimidine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, ((2-bromoethoxy)methyl)- | HCID 73833 | — |
| Reactant | N2,N4-bis(3-aminophenyl)-5-fluoro-2,4-primidinediamine | HCID 10215022 | — |
| Product | 5-Fluoropyrimidine-2,4-diamine | HCID 255608 | — |
Reaction Steps
In like manner to the preparation of N2,N4-bis(3-tert-butoxycarbonylmethyleneaminophenyl)-5-fluoro-2,4-pyrimidinediamine, N2,N4-bis(3-aminophenyl)-5-fluoro-2,4-pyrimidinediamine and 1-benzyloxy-2-bromoethane were reacted together to give N2,N4-bis[3-N-benzyloxyethyleneamino)phenyl]-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 32.92 min.; MS (m/e): 579.17 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589200B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2f18ac869c594e81b1d22cf1162e74ea |
| Source note | uspto-grants-2009_09 |