HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734147Generated: October 29, 2026
Potassium Carbonate → HCID 23104613, compound
https://huagongshe.com/reaction/734147
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| Reactant | 3-Amino-1,2-propanediol | HCID 73561 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 23104613 | HCID 23104613 | 68.6% |
Reaction Steps
2 g of 2-fluoro-5-nitrotoluene were added to a solution of 20 ml of N-methylpyrrolidinone, 1.4 g of 2,3-dihydroxy-1-propylamine, and 2.14 g of K2CO3. The reaction medium was heated at 60° C. for 15 hours and, after cooling to room temperature, was poured into a water/ice mixture. A yellow precipitate formed, which was filtered off, reslurried in water and then dried over P2O5. 2 g of 3-(4-nitro-2-methylphenylamino)propane-1,2-diol (7) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07591860B2 |
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| Source dataset | uspto-grants-2009_09 |
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| ORD ID | ord-0b6eefbb3b8f4a58aedef35e88d93df0 |
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| Source note | uspto-grants-2009_09 |
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