Potassium Carbonate → HCID 11955931, compound

Participants

Reaction Steps

To the compound 2-[6-(4-{5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)hexahydropyrrolo[3,4-b][1,4]oxazin-4(4aH)-yl]-2-oxoethyl acetate (590 mg) obtained from Example 06 above in methanol (15 ml) was added potassium carbonate (0.34 g) and stirred for overnight. The reaction mixture was filtered, concentrated and purified by column using 3% methanol in dichloromethane as eluant to yield the title compound (300 mg).

Provenance & Evidence