HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-1-isopropyl-4-(piperidine-4-carbonyl)-2-methylpiperazine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (S)-1-isopropyl-4-[1-(tert-Butoxycarbonyl)-piperidine-4-carbonyl]-2-methyl piperazine | HCID 68818623 | — |
| Product | (S)-1-isopropyl-4-(piperidine-4-carbonyl)-2-methylpiperazine dihydrochloride | HCID 68817427 | — |
Reaction Steps
(S)-1-Isopropyl-4-[1-(tert-butoxycarbonyl)-piperidine-4-carbonyl]-2-methyl-piperazine (D28)(3.8 g) was treated with HCl as described in Description 8 step 4 to give the title dihydrochloride (D29) as a white solid (2.5 g). LCMS electrospray (+ve) 254 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592347B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-16f4f6702ce24916a36e8702dc9189cd |
| Source note | uspto-grants-2009_09 |