HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline → 3-{2-[4-(7-Chloro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| Reactant | 7-Chloro-2-methyl-5-{4-[2-(3-nitrophenyl)ethyl]-1-piperazinyl}quinoline | HCID 57444276 | — |
| Product | 3-{2-[4-(7-Chloro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 57444309 | 92% |
Reaction Steps
The title compound was prepared in 92% yield using a similar procedure to description D6 starting from 7-Chloro-2-methyl-5-{4-[2-(3-nitrophenyl)ethyl]-1-piperazinyl}quinoline (D17).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592346B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-22e46e6eb61f4aa88f5588dd4d5bea74 |
| Source note | uspto-grants-2009_09 |