Ethanesulfonyl chloride → HCID 11284107, compound

HRID 734747Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([CH:12]2[CH2:17][C:16](=[O:18])[NH:15][C:14]([CH3:19])=[C:13]2[C:20]([NH:22][C:23]2[CH:24]=[C:25]3[C:29](=[CH:30][C:31]=2[F:32])[NH:28][N:27]=[CH:26]3)=[O:21])[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[CH2:33]([S:35](Cl)(=[O:37])=[O:36])[CH3:34]>>[CH2:33]([S:35]([NH:1][C:2]1[CH:3]=[C:4]([CH:12]2[CH2:17][C:16](=[O:18])[NH:15][C:14]([CH3:19])=[C:13]2[C:20]([NH:22][C:23]2[CH:24]=[C:25]3[C:29](=[CH:30][C:31]=2[F:32])[NH:28][N:27]=[CH:26]3)=[O:21])[CH:5]=[CH:6][C:7]=1[C:8]([F:10])([F:11])[F:9])(=[O:37])=[O:36])[CH3:34]

Participants

Reactant 2

HCID 11667Ethanesulfonyl chloride

HCID 57845274HCID 57845274, compound

Product 1

HCID 11284107HCID 11284107, compound

Procedure

The title compound was prepared according to the procedure described in Example 78, beginning with the product from Example 80 and using ethanesulfonyl chloride in place of methanesulfonyl chloride. MS (ES+) m/e 414 [M+H]+.

Sources & evidence

ORD record: ord-1c0a5d32c1644dafb2face7486707b5e
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07592357B2

Reaction notes

Loading…