HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl acetate methanol ammonia → 4-Isopropylpiperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl acetate methanol ammonia | HCID 21873639 | — |
| Reactant | 1-Benzyl-4-isopropylpiperidin-4-ol | HCID 69061443 | — |
| Product | 4-Isopropylpiperidin-4-ol | HCID 57416290 | — |
Reaction Steps
The product was obtained analogously to Example IP 5d from 9.85 g (42.2 mmol) of 1-benzyl-4-isopropylpiperidin-4-ol. Yield: 1.13 g (19% of theoretical); C8H17NO (M=143.227); calc.: molpeak (M+H)+: 144; found: molpeak (M+H)+: 144; Rf value: 0.07 (silica gel, EtOAc/MeOH/NH3 5:5:0.5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-0508f6b455694593bf5756569bcc7b1f |
| Source note | uspto-grants-2009_09 |