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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734817Generated: October 27, 2026

BROMINE CHLORIDE (BrCl) → 3-Bromo-5-(4-chlorophenyl)-2-ethynylpyridine

https://huagongshe.com/reaction/734817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBROMINE CHLORIDE (BrCl)HCID 61697—
ReactantHCID 69057764HCID 69057764—
Product3-Bromo-5-(4-chlorophenyl)-2-ethynylpyridineHCID 86077051—

Reaction Steps

The product was prepared analogously to Example 7.1d starting from 3-bromo-5-(4-chlorophenyl)-2-trimethylsilanylethynylpyridine. Yield: 0.44 g (55% of theoretical); C13H7BrClN (M=292.558); calc.: molpeak (M+H)+: 292/294/296 (BrCl); found: molpeak (M+H)+: 292/294/296 (BrCl); HPLC-MS: 6.21 minutes (method B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592358B2
Source datasetuspto-grants-2009_09
ORD IDord-1856f18b2f2840a2bf7cacf40ea1befb
Source noteuspto-grants-2009_09