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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734819Generated: October 29, 2026

BROMINE CHLORIDE (BrCl) → HCID 11598674, compound

https://huagongshe.com/reaction/734819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBROMINE CHLORIDE (BrCl)HCID 61697—
Reactant4-MethylpiperidineHCID 69381—
Reactant2-{4-[3-Bromo-5-(4-chlorophenyl)pyridin-2-ylethynyl]phenoxy}ethyl methanesulfonateHCID 86601136—
ProductHCID 11598674HCID 11598674—

Reaction Steps

The product was obtained analogously to Example 7.1g starting from 2-{4-[3-bromo-5-(4-chlorophenyl)pyridin-2-ylethynyl]phenoxy}ethyl methanesulfonate and 4-methylpiperidine. Yield: 0.15 g (88% of theoretical); C27H26BrClN2O (M=509.865); calc.: molpeak (M+H)+: 509/511/513 (BrCl); found: molpeak (M+H)+: 509/511/513 (BrCl); HPLC-MS: 6.11 minutes (method A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592358B2
Source datasetuspto-grants-2009_09
ORD IDord-d489ea53f8714d32a264a680867b3f81
Source noteuspto-grants-2009_09