HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilylacetylene → 5-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridin-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | 2-Bromo-5-(4-chloro-phenyl)-pyridin-3-ylamine | HCID 85969704 | — |
| Product | 5-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridin-3-ylamine | HCID 69059378 | — |
Reaction Steps
The product was obtained analogously to Example 7.1b starting from 2-bromo-5-(4-chlorophenyl)pyridin-3-ylamine (Example 16.1c) and trimethylsilylacetylene. Yield: 1.09 g (51% of theoretical); C16H17ClN2Si (M=300.858); calc.: molpeak (M+H)+: 301/303 (Cl); found: molpeak (M+H)+: 301/303 (Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-235b3c1a957d4cf49524ff782ba84a44 |
| Source note | uspto-grants-2009_09 |