HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-ethynylpyridine → 5-Bromo-2-{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylethynyl}pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-ethynylpyridine | HCID 13979734 | — |
| Reactant | 1-(2-(4-Iodophenoxy)ethyl)-4-methylpiperidine | HCID 69061017 | — |
| Product | 5-Bromo-2-{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylethynyl}pyridine | HCID 69060172 | — |
Reaction Steps
The product was prepared analogously to Example 7.1e starting from 1-[2-(4-iodophenoxy)ethyl]-4-methylpiperidine and 5-bromo-2-ethynylpyridine. Yield: 1.00 g (62% of theoretical); C21H23BrN2O (M=399.324); calc.: molpeak (M+H)+: 399/401 (Br); found: molpeak (M+H)+: 399/401 (Br); HPLC-MS: 4.64 minutes (method A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-0f7a4ea2137e413383059d1b9849b56d |
| Source note | uspto-grants-2009_09 |