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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 734845Erstellt: 25. Oktober 2026

2-(4-Methylpiperidin-1-yl)ethan-1-amine → {5-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]thiophen-3-yl}-[2-(4-methylpiperidin-1-yl)ethyl]amine

https://huagongshe.com/reaction/734845

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(4-Methylpiperidin-1-yl)ethan-1-amineHCID 783700—
Edukt5-(4-Chlorophenyl)-2-(4-iodothiophen-2-ylethynyl)pyridineHCID 69056001—
Produkt{5-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]thiophen-3-yl}-[2-(4-methylpiperidin-1-yl)ethyl]amineHCID 57845298—

Reaktionsschritte

The product was obtained analogously to Example 20.1a starting from 5-(4-chlorophenyl)-2-(4-iodothiophen-2-ylethynyl)pyridine and 2-(4-methylpiperidin-1-yl)ethylamine. Yield: 3 mg (1% of theoretical); C25H26ClN3S (M=436.013); calc.: molpeak (M+H)+: 436/438 (Cl); found: molpeak (M+H)+: 436/438 (Cl); HPLC-MS: 5.10 minutes (method B).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07592358B2
Quelldatensatzuspto-grants-2009_09
ORD IDord-8be79240460d447bb4976a1567b727df
Quellennotizuspto-grants-2009_09