HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilylacetylene → [5-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridin-3-yl]dimethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | [2-Bromo-5-(4-chlorophenyl)pyridin-3-yl]dimethylamine | HCID 86076948 | — |
| Product | [5-(4-Chlorophenyl)-2-trimethylsilanylethynylpyridin-3-yl]dimethylamine | HCID 69058189 | — |
Reaction Steps
The product was prepared analogously to Example 7.1c starting from [2-bromo-5-(4-chlorophenyl)pyridin-3-yl]dimethylamine and trimethylsilylacetylene. Yield: 0.50 g (quant. yield); C18H21ClN2Si (M=328.911); calc.: molpeak (M+H)+:329/331 (Cl); found: molpeak (M+H)+:329/331 (Cl); HPLC-MS: 7.41 minutes (method B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-7c6719280e8e489d87b94949cfb14547 |
| Source note | uspto-grants-2009_09 |