HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyrazine → HCID 22248974, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyrazine | HCID 599539 | — |
| Reactant | HCID 69063338 | HCID 69063338 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 22248974 | HCID 22248974 | — |
Reaction Steps
The product was prepared analogously to Example 48.1a from 2.61 g (15.0 mmol) of 5-bromopyrazin-2-ylamine and 2.56 g (15.0 mmol) of 4-chloro-2-methylphenylboric acid. Yield: 1.70 g (52% of theoretical); C11H10ClN3 (M=219.670); calc.: molpeak (M+H)+:220/222 (Cl); found: molpeak (M+H)+:220/222 (Cl); Rf value: 0.35 (silica gel, PE/EtOAc 7:3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-97d07e8aee87498595e29665c65ffd68 |
| Source note | uspto-grants-2009_09 |